TIPS Shunt Creation With Chronic Portal Vein Occlusion

Larry Rufer, M.D.

Fig. 1. Transhepatic portogram demonstrating cavernous collaterals.

Fig. 2. Transjugular portogram via RHV to RPV puncture.

Case Reference No. CC-0400-07

A 48-year-old white male Pugh-Child Class B EtOH cirrhotic with marked ascites who had quit drinking 5 years earlier presented to us after repeated acute variceal hemorrhages. The bleeding was managed tenuously endoscopically however he had a slow persistent drop in Hgb.

We initially attempted transhepatic PV recanalization (fig 1), but were unsuccessful. A 5f catheter was left in place and transjugular access was achieved into the intrahepatic RPV (fig 2). TIPS shunt was created between RHV, RPV, and a large cavernous collateral with reduction of initial PV/RA gradient of 30 mmHg to a final PV/RA gradient of 8 mmHg (fig 3). Finally, injection of the previously placed transhepatic catheter in a cavernous collateral revealed outflow through the TIPS (fig 4).

The patient was discharged on the second post-procedural day and was re-admitted for 23 hour admit on the following day for new onset encephalopathy which was successfully medically treated. It was also noted at the re-admission that there was significant reduction in the patient’s abdominal girth and relayed by his wife that he had been putting out copious amounts of urine. At two months post-procedure he has not re-bled and his abdomen is flat and encephalopathy is controlled.

Fig. 3. Transjugular portogram after TIPS shunt placement. Final PV/RA gradient 8mmHg.

Fig. 4. Transhepatic portogram after TIPS placement showing flow from large collaterals in liver hilum out through TIPS shunt.

Questions:

1) What is your experience with chronic PV occlusion and TIPS if the PV cannot be recanalized?

2) Describe your thoughts about alternative approaches to PV recanalization such as mini-lap or trans-splenic route.

3) Have you found creating a TIPS to a cavernous collateral to be a viable option in a similar case or cases?

4) What kind of follow-up should be obtained?

Reference:

Yamagami T, et al. Transjugular Intrahepatic Portosystemic Shunt after Complete Obstruction of Portal Vein. JVIR 1999; 10:575-578.

Related cases:

Case 1097_02 -- Portal vein thrombosis in the setting of acute pancreatitis: treatment with portal reconstruction

Case 0100_06 -- Management of Acute Liver Failure in a Patient with Portal and Hepatic Vein Thrombosis

Case 0300_06 -- Transsplenic Portal Vein Recanalization in a Patient With Bleeding Varices